Akinetic swept-source optical coherence tomography based on a pulse-modulated active mode locking fiber laser for human retinal imaging

Abstract

Optical coherence tomography (OCT) is a noninvasive imaging modality that can provide highresolution, cross-sectional images of tissues. Especially in retinal imaging, OCT has become one of the most valuable imaging tools for diagnosing eye diseases. Considering the scattering and absorption properties of the eye, the 1000-nm OCT system is preferred for retinal imaging. In this study, we describe the use of an akinetic swept-source OCT system based on a pulse-modulated active mode locking (AML) fber laser at a 1080-nm wavelength for in-vivo human retinal imaging. The akinetic AML wavelength-swept fber laser was constructed with polarization-maintaining fber that has an average linewidth of 0.625nm, a spectral bandwidth of 81.15nm, and duty ratio of 90% without the bufering method. We successfully obtained in-vivo human retinal images using the proposed OCT system without the additional k-clock and the frequency shifter that provides a wide feld of view of 43.1°. The main retina layers, such as the retinal pigment epithelium, can be distinguished from the OCT image with an axial resolution of 6.3 μm with this OCT system.