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GIST Repository College of Natural Sciences Department of Chemistry 1. Journal Articles

An AIE-based fluorescent probe to detect peroxynitrite levels in human serum and its cellular imaging

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Author(s)
Kim, Jaewon; Yoo, Jiyoung; Kim, Byungkook; Lee, Kyung-Woo; Kim, Sunghyun; Hong, Sukwon; Kim, Jong Seung
Type
Article
Citation
Chemical Communications, v.60, no.41, pp.5443 - 5446
Issued Date
2024-05
Abstract
An AIE-based fluorescent probe was designed to evaluate peroxynitrite levels in complex biological samples. The newly synthesized hydrazone-conjugated probe fluoresces strongly in the presence of peroxynitrite. Clinically, the peroxynitrite levels can be measured in human serum and cellular mitochondria with an LOD of 6.5 nM by fluorescence imaging in vitro. © 2024 The Royal Society of Chemistry.
Publisher
Royal Society of Chemistry
ISSN
1359-7345
DOI
10.1039/d4cc01231c
URI
https://scholar.gist.ac.kr/handle/local/9572
Appears in Collections:
Department of Chemistry > 1. Journal Articles
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