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GIST Scholar College of Life Sciences and Medical Engineering Department of Life Sciences 1. Journal Articles

Histamine Signaling Is Essential for Tissue Macrophage Differentiation and Suppression of Bacterial Overgrowth in the Stomach

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Author(s)
Kim K.H.; Park, Jihwan; Cho Y.; Cho S.Y.; Lee B.; Jeong H.; Lee Y.; Yi J.-W.; Oh Y.; Lee J.-J.; Wang T.C.; Lim K.-M.; Nam K.T.
Type
Article
Citation
Cellular and Molecular Gastroenterology and Hepatology, v.15, no.1, pp.213 - 236
Issued Date
2022-09
Abstract
Background & Aims: Histamine in the stomach traditionally is considered to regulate acid secretion but also has been reported to participate in macrophage differentiation, which plays an important role in tissue homeostasis. Therefore, this study aimed to uncover the precise role of histamine in mediating macrophage differentiation and in maintaining stomach homeostasis. Methods: Here, we expand on this role using histidine decarboxylase knockout (Hdc
Publisher
Elsevier Inc.
ISSN
2352-345X
DOI
10.1016/j.jcmgh.2022.09.008
URI
https://scholar.gist.ac.kr/handle/local/8664
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