전립선암의 조기 발견과 영상 진단의 정확도 향상을 위한 다채널 근적외선분광 시스템의 개발: 팬텀 연구

Abstract

Purpose: The purpose of this study was to develop a multi-channel NIRS (Near-Infrared Spectroscopy) system and verify its diagnostic capability for the early detection and improvement of the accuracy of imaging diagnosis of prostate cancer. Materials and Methods: We developed a new multi-channel NIRS system using two near-infrared wavelengths - 785 nm and 830 nm. Each wavelength had 8 channels and shared 2 detectors. A computer software named Labview (National Instrument, USA) was used to develop GUI (Graphic User Interface) which can process incoming signals and display them on the same monitor simultaneously. We applied our NIRS system to the optical phantoms of the prostate gland and prostate cancer to verify its diagnostic capability. Results: Relatively lower light signal intensities were noted around three surface channels over prostate cancer model at both detectors and at both wavelengths, suggesting that light is more absorbed and/or scattered when passing through these routes reflecting the presence of an inner region with different optical properties from its surroundings. Conclusion: We successfully demonstrated the possibility of the NIRS system as a new potential imaging method for improving the diagnostic accuracy of prostate cancer.