Identification of new arylsulfide derivatives as anti-melanogenic agents in a zebrafish model
- Type
- Article
- Citation
- Bioorganic and Medicinal Chemistry Letters, v.30, no.13
- Issued Date
- 2020-04
- Abstract
- A series of aryl sulfide derivatives was synthesized and evaluated for their anti-melanogenic activities. Several compounds, including 3e, 3i and 3q exhibited good anti-melanogenic activities. Among the derivatives, compound 3i showed good inhibitory effects against melanin synthesis and showed no toxicity in reconstituted human eye and skin tissues. © 2020 Elsevier Ltd
- Publisher
- Elsevier Ltd
- ISSN
- 0960-894X
- Appears in Collections:
- Department of Chemistry > 1. Journal Articles
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